Fa'amatalaga
Topirastat intermediate 2-cyanoisonicotinic acid, CAS Numera 161233-97-2.O lenei oloa e lauiloa foi i isi igoa: 2-cyanopyridine-4-carboxylic acid, 2-cyano-4-pyridinecarboxylic acid, ma le 4-pyridinecarboxylic acid, 2-cyano-.O le fua mole mole o lenei tuufaatasiga o le C7H4N2O2 ma le mamafa mole e 148.1189.O se vaega taua i le tuʻufaʻatasia o le topirastat (o se vailaʻau faʻaaogaina e togafitia ai le hyperuricemia i gasegase gout).
2-Cyanoisonicotinic acid e taua tele i le gaosiga o le topirastat, lea e galue e ala i le taofia o le xanthine oxidase, o se enzyme e aʻafia i le gaosiga o le uric acid.O le i'uga, ua fa'aitiitia le maualuga o le uric acid i totonu o le toto, ma fa'amalolo ai fa'ailoga o tagata mama'i gout.O lenei faʻalapotopotoga faʻapitoa o se mea taua i le gaosiga o le gaosiga o le topirastat, ma avea ai ma vaega taua o le falemaʻi vailaʻau.
Filifili Matou
O le JDK o lo'o i ai le vaega muamua o le gaosiga o fale ma meafaigaluega tau pulega lelei, lea e fa'amautinoa ai le tu'uina atu o le API intermediates.'Au fa'apolofesa fa'amautinoa le R&D o le oloa.Faʻasaga ia lua, o loʻo matou suʻeina CMO & CDMO i maketi i totonu o le atunuʻu ma faavaomalo.
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